Early ISS experimentation is constrained by limited availability of astronaut support and automated ISS hardware. The CCM-C is a fully automated bioreactor-based system that features a 4° - 8° C cooling chamber and can be configured for Express Rack accommodation to perform extended duration ISS experiment. Experiments can be performed in the fields of:

Radiobiology Long-term growth, differentiation Gene expression and regulation Alterations in cell cycle

Cell fusion Mineralization /Crystalization Cell attachment factors Cell physiology and organization

The CCM-C uses a variety of programmed events to execute experiment protocols. By combining basic operations into sequences, standard laboratory manipulations can be accomplished including:

Typical Experiment Scheme

A baseline quiescent sample is collected prior to on-orbit activation. The samples are radio (chemically) labeled and protein accumulation is measured in discrete time units.